
Blinded evaluators correctly identified the before and after photos in all cases. There was statistically and clinically significant improvement in the Fitzpatrick classification of the periorbital wrinkles. Patients were asked to answer a questionnaire measuring satisfaction 4 weeks after each session, and to report any adverse reactions. Reviewers were asked to determine the before and after photos. Blind photographic evaluations were performed by three independent physicians using unlabeled before and after photos arranged in non-chronological order. Patient improvement was assessed before each laser session as well as at 12 months after the final treatment. The treatment sessions were performed on each patient, 4 weeks apart. All patients were assessed according to Fitzpatrick’s classification of periorbital wrinkles to class I, II, or III and were treated with 2940 nm Er:YAG laser using a fluence of 3.75 J/cm 2, a repetition rate of 1.7–2 Hz, and with the SMOOTH™ pulse mode (250 ms). This is a prospective analysis of 30 patients treated for periorbital rejuvenation using three sessions of non-ablative long-pulse Er:YAG laser over a 3-month period. The objective of this study is to evaluate the safety and efficacy of long-pulse 2940 nm Er:YAG laser for non-ablative treatment of periorbital static wrinkles and skin laxity. More recently, the non-ablative long-pulse 2940 nm Er:YAG laser is being used to improve the structure and function and hence the appearance of skin in the periorbital region. Although effective, the associated downtime with these methods has made many people reluctant to decide for such treatments. Surgery and laser resurfacing have traditionally been used to correct periorbital lines and wrinkles.

The periocular region is challenging for cosmetic laser surgeons.
